11/22/2023 0 Comments Second degree burn![]() ![]() The scientific name and the quality were confirmed with a quality assurance number obtained from the School of Pharmacy, Shahid Sadoughi University of Medical Sciences (SSU0042). officinalis flowers were obtained from Yazd medicinal plants market. All mice were observed according to the animal rights ethics protocol of Yazd Shahid Sadoughi University of Medical Sciences (IR.1398.055). The animals were housed in groups of six in standard laboratory conditions at 18 to 23☌ and 40 - 60% humidity, and they were kept in separated cages for 12 hours, light/dark cycle, and free access to standard food and tap water. Male NMRI mice (25 - 30 g, two months old) were purchased from the animal house of the School of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. officinalis on reducing inflammation and accelerate the wound healing process. ![]() The present study aimed to investigate the effects of aqueous and hydroalcoholic extracts of A. Its effectiveness in treating skin diseases such as eczema has been reported to result from its phagocytosis and macrophage activation ( 8). The pectin in Althaea officinalis has an immune-stimulating and wound-healing effect ( 7). Using medicinal plants has been recently welcomed to medicine for therapeutic purposes ( 6). Accordingly, it is crucial to identify therapeutic agents for a faster repair of the dermis and epidermis against skin damage. Although antibacterial medications such as topical silver sulfadiazine may prevent wound infections, they usually cannot accelerate skin healing ( 5). Injured skin may be infected by cutaneous flora and other pathogens. Following damage to the skin, the lower layer cells of the dermis begin to build collagen and repair the epithelial cells ( 4). Superficial cells that are lost due to wear, damage, or disease are rapidly replaced. The skin is constantly renewed by shedding dead cells and producing new cells. This barrier is most effective when it is not damaged. Skin is a protective barrier against microorganisms and harmful substances ( 3). When skin damage involves the dermis in addition to the epidermis, it causes second-degree burns, and when all layers of the skin are damaged, third-degree burns occur ( 2). Burns are usually classified according to their severity and weakness. More than 6.6 million people are estimated to suffer from burns worldwide ( 1). Backgroundīurns are one of the most common injuries. Conclusions: Althaea officinalis may have been used as an adjunct medication to accelerate wound healing in skin burns.Īlthaea Officinalis Second-degree Burn Wound Healing Mice 1. ![]()
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